Videoplaza has launched Karbon 2, the new version of its video ad-serving technology. The big news is that Videoplaza now enables publishers to do audience-based targeting in addition to content-based targeting. Its done by allowing publishers connecting its own or third-parties (like Nugg.Ad, Meetrics, Enreach, Eyota and Bluekai) data to the ad-server. It's not an out-of-the-box solution, but rather targeted towards the higher-end of online video publishers.
(Disclosure: I'm an investor in and former board member of Videoplaza.)